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Las glándulas paratiroides son cuatro glándulas diminutas incrustadas en la parte posterior de la glándula tiroides. Las glándulas paratiroideas secretan hormona paratiroidea cuando los niveles de calcio en el el cuerpo es bajo. La PTH, junto con la vitamina D, eleva los niveles plasmáticos de calcio al incrementar la actividad de osteoclastos, que da como resultado la liberación de calcio de los huesos; aumentando la reabsorción de calcio por el riñón y aumentando la absorción de calcio del intestino.
La deficiencia de PTH se trata con inyecciones de calcio y calcitriol (una vitamina D término análogo). Los niveles altos de calcio en el plasma sanguíneo provocan la liberación de calcitonina de la tiroides.
Psoralen provoca la estimulación de melanocitos y algo de repigmentación en el vitiligo. Los corticosteroides tópicos no deben usarse durante períodos prolongados o en áreas extensas de psoriasis porque su abstinencia puede producir una reacción de rebote y cambios a largo plazo en la estructura de la piel. Sin embargo, los corticosteroides siguen siendo útiles para lesiones pequeñas.
Combinatorio Los corticosteroides con otro tratamiento tópico son eficaces en algunos casos. Estos medicamentos están reservados para pacientes con las formas más graves de psoriasis que no responden a, o no pueden tolerar, tópicos o fototerapia.